Medication Basics
Generic Name: Hydralazine
Brand Name: Apresoline
Medication Class: Vasodilator
Description
Hydralazine is a medication which directly acts on muscle surrounding blood vessels to cause relaxation. This helps to lower blood pressure and reduce workload on the heart. As a result of this, hydralazine is therapeutically used in hypertension and in chronic or congestive heart failure (in combination with a nitrate). Since hydralazine is short acting, it must be dosed frequently throughout the day which will often make the medication less preferred for initial therapy compared to other options. It does, however, maintain a strong role in high blood pressure unresponsive to other medications and in the treatment of heart failure, particularly in combination with a nitrate in African Americans.
When might my doctor prescribe this medication?
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High blood pressure (or hypertension)
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Chronic or congestive heart failure
I should NOT take this medication if:
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I have had severe allergic reactions to hydralazine in the past
Adverse Effects (common)
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Dizziness
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Leg swelling (or edema)
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Fast heart rate
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Chest pain
Adverse Effects (rare, but serious)
Common Adult Doses and Forms
Hydralazine (Apresoline): 25 mg to 100 mg three times daily
Dosage Forms:
Hydralazine (Apresoline): 10 mg, 25 mg, 50 mg, 100 mg
How should I take this medication?
Hydralazine should be taken with a small snack or food.
Please note that the content on CardioSmart is a summary of the most generally pertinent information about this drug but does not cover every side effect or precaution. However, everyone is unique, and the extent to which the information applies specifically to you should be a key point of discussion between you and your cardiologist or health care provider. The ultimate judgment regarding your care must be made by you and your healthcare provider together, in light of circumstances specific to you as a patient.
