Angina

Clinical Trial Finder

Many patients with angina are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Optical Coherence Tomography to Investigate FFR-Guided DEB-only Elective Coronary Angioplasty

Conditions:   Stable Angina;   Coronary Stenosis
Interventions:   Device: FFR - guided DEB angioplasty;   Device: Provisional bare metal stenting
Sponsors:   University of Jena;   B. Braun Melsungen AG
Completed - verified April 2014

Study to Detect Biomarker Gradients in Coronary Arteries Using the Liquid Biopsy System

Condition:   Coronary Heart Disease
Intervention:  
Sponsors:   PlaqueTec Ltd;   Papworth Hospital NHS Foundation Trust
Not yet recruiting - verified April 2014

Multicenter, Prospective, Randomized, Controlled, Double-blind Trial on the Impact of Rosuvastatin on Subclinical Markers of Atherosclerosis in Patients With Primary Necrotizing Vasculitides

Condition:   ANCA-associated Primary Necrotizing Vasculitides
Interventions:   Drug: Rosuvastatin;   Drug: Placebo
Sponsor:   Assistance Publique - Hôpitaux de Paris
Not yet recruiting - verified April 2014

Mi-RNAs and Specificity of Hs-TnT in Symptomatic ED Patients

Conditions:   Coronary Artery Disease;   Myocardial Infarction
Intervention:  
Sponsors:   University Hospital Heidelberg;   German Heart Research Foundation
Not yet recruiting - verified April 2014

The Effect of Clopidogrel and Ticagrelor With and Without Acetylsalicylic Acid (ASA) on Hemostatic System Activation at the Site of Plug Formation in Vivo in Man

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Clopidogrel;   Drug: Ticagrelor;   Drug: ASA;   Drug: Placebo
Sponsor:   Medical University of Vienna
Completed - verified April 2014

The Safety and Efficacy of 'AVI' Stent for Treating Coronary Revascularization

Conditions:   Ischemic Heart Disease;   Myocardial Ischemia;   Coronary Disease;   Acute Coronary Syndrome
Intervention:   Device: AVI® Arsenic trioxide drug eluting stent
Sponsor:   Beijing AmsinoMed Medical Device Co., Ltd
Recruiting - verified April 2014

Prognostic Value of Biomarkers Associated With Endothelial Progenitor Cells Mobilization in Acute Coronary Syndromes

Condition:   Acute Coronary Syndromes
Intervention:   Other: blood sample
Sponsor:   Assistance Publique Hopitaux De Marseille
Not yet recruiting - verified April 2014

Copeptin Testing During Pre-hospital Care in the Treatment of Chest Pain Suggestive of Acute Coronary Syndrome

Condition:   Chest Pain
Interventions:   Biological: Blood work in the ambulance;   Biological: Blood work upon arrival in the emergency room;   Biological: Blood work at 3 hours post-arrival in the emergency room
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Not yet recruiting - verified April 2014

DIAMOND - Dual Antiplatelet Therapy to Reduce Myocardial Injury

Condition:   Coronary Artery Disease
Interventions:   Drug: Ticagrelor;   Drug: Placebo
Sponsors:   University of Edinburgh;   AstraZeneca
Not yet recruiting - verified April 2014

Assessment of the Effect of Atorvastatin on Prevention of CIN in Patients Undergoing Coronary Angiography

Condition:   Contrast Induced Nephropathy
Intervention:   Drug: Atorvastatin
Sponsor:   Isfahan University of Medical Sciences
Recruiting - verified April 2014

Short-term Dual Anti Platelet Therapy in Patients With ACS Treated With the COMBO Dual-therapy Stent

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Treatment 3 months DAPT;   Drug: Treatment 12 months DAPT
Sponsor:   Diagram B.V.
Not yet recruiting - verified April 2014

Antiplatelet Therapy Following Stent Implantation

Conditions:   Acute Myocardial Infarction;   Coronary Syndrome;   Angina, Unstable
Intervention:  
Sponsor:   Elpen Pharmaceutical Co. Inc.
Recruiting - verified January 2014

BIOFLOW III Satellite-Italy

Condition:   Coronary Artery Diseases
Intervention:  
Sponsor:   Biotronik Italia S.p.A.
Recruiting - verified January 2014

BIOFLOW III Satellite-ELADIS

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   C.E.M. Biotronik, S.A.
Recruiting - verified February 2014

Cardiovascular Outcomes Following Treatment With Ertugliflozin in Participants With Type 2 Diabetes Mellitus and Established Vascular Disease (MK-8835-004)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Ertugliflozin;   Drug: Placebo
Sponsors:   Merck Sharp & Dohme Corp.;   Pfizer
Recruiting - verified April 2014

HsTnT in Stable Coronary Artery Disease

Condition:   Coronary Artery Disease
Intervention:   Other: Progress of CHD
Sponsors:   University Hospital Heidelberg;   AstraZeneca
Active, not recruiting - verified April 2014

In-hospital and Long-term Outcomes for Percutaneous Chronic Total Coronary Occlusion Revascularization in a High-volume, Multi-operator Program

Condition:   Ischemic Heart Disease
Intervention:  
Sponsor:   Piedmont Healthcare
Recruiting - verified April 2014

The LADIES Acute Coronary Syndromes Study

Conditions:   Acute Coronary Syndromes;   Menopause
Intervention:  
Sponsor:   Arcispedale Santa Maria Nuova-IRCCS
Recruiting - verified April 2014

CARMELINA: Cardiovascular and Renal Microvascular Outcome Study With Linagliptin in Patients With Type 2 Diabetes Mellitus at High Vascular Risk

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Placebo;   Drug: Linagliptin
Sponsors:   Boehringer Ingelheim;   Eli Lilly and Company
Recruiting - verified April 2014

BIOFLOW-III Belgium Satellite Registry

Conditions:   Coronary Artery Disease;   Myocardial Ischemia
Intervention:  
Sponsor:   Biotronik Belgium NV
Recruiting - verified April 2013

The Elderly ACS II Trial

Conditions:   Acute Coronary Syndrome;   Coronary Arteriosclerosis;   Myocardial Ischemia;   Cardiovascular Diseases
Interventions:   Drug: prasugrel;   Drug: Clopidogrel
Sponsors:   Arcispedale Santa Maria Nuova-IRCCS;   ANMCO Italian Association of Hospital Cardiologist;   Italian Society of Invasive Cardiology
Recruiting - verified April 2014

Tailored Antiplatelet Therapy Following PCI

Conditions:   Coronary Artery Disease;   Acute Coronary Syndrome;   Stenosis
Interventions:   Drug: Clopidogrel;   Drug: Ticagrelor;   Genetic: Retrospective Genotype testing;   Genetic: Prospective Genotype testing
Sponsors:   Mayo Clinic;   Applied Health Research Centre (AHRC), Toronto, Canada
Recruiting - verified April 2014

A Study to Assess Cardiovascular Outcomes Following Treatment With MK-3102 in Participants With Type 2 Diabetes Mellitus (MK-3102-018)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: MK-3102;   Drug: Placebo
Sponsor:   Merck Sharp & Dohme Corp.
Recruiting - verified April 2014

Danhong Injection in the Treatment of Chronic Stable Angina

Condition:   Chronic Stable Angina
Interventions:   Drug: Danhong injection;   Other: Standard medical care;   Drug: Placebo
Sponsors:   China Academy of Chinese Medical Sciences;   China: State Food and Drug Administration
Recruiting - verified April 2014

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab SAR236553 (REGN727)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: alirocumab SAR236553 (REGN727);   Other: placebo
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified April 2014

ProspEctive First Evaluation in Chest Pain Trial

Conditions:   Chest Pain;   Shortness of Breath;   Suspected Acute Coronary Syndrome
Interventions:   Procedure: Coronary CT Angiography;   Procedure: Stress Test
Sponsor:   St. Luke's-Roosevelt Hospital Center
Recruiting - verified May 2012

Study To Evaluate Cardiac Assessments Following Different Treatments Of Smoking Cessation Medications In Subjects With And Without Psychiatric Disorders.

Condition:   Smoking Cessation
Interventions:   Drug: placebo;   Drug: varenicline tartrate;   Drug: bupropion hydrochloride;   Drug: Nicotine Replacement Therapy Patch
Sponsor:   Pfizer
Recruiting - verified April 2014

A Study to Evaluate Cardiovascular Outcomes in Patients With Type 2 Diabetes Treated With ITCA 650

Condition:   Type 2 Diabetes
Interventions:   Drug: ITCA 650;   Other: ITCA placebo
Sponsor:   Intarcia Therapeutics
Recruiting - verified April 2014

Clearance Of Mucus In Stents

Conditions:   Lung Neoplasms;   Respiratory Failure;   Pneumonia;   Acute Coronary Syndromes;   Unstable Angina;   Myocardial Infarction;   Cardiac Arrhythmia;   Thromboembolic Disease
Interventions:   Other: Normal Saline;   Other: Sodium Bicarbonate
Sponsor:   M.D. Anderson Cancer Center
Recruiting - verified April 2014

"Spot Sign" Selection of Intracerebral Hemorrhage to Guide Hemostatic Therapy

Condition:   Stroke
Interventions:   Biological: rfVIIa;   Other: Standard saline solution
Sponsors:   Sunnybrook Health Sciences Centre;   Dr. David Gladstone;   Canadian Institutes of Health Research (CIHR)
Recruiting - verified March 2014

A Study of RoActemra/Actemra (Tocilizumab) in Comparison to Etanercept in Patients With Rheumatoid Arthritis and Cardiovascular Disease Risk Factors

Condition:   Cardiovascular Disease, Rheumatoid Arthritis
Interventions:   Drug: tocilizumab [RoActemra/Actemra];   Drug: etanercept
Sponsor:   Hoffmann-La Roche
Active, not recruiting - verified April 2014

Post-authorization Safety Study of Etoricoxib and Other Anti-inflammatory Therapies in European Patients With Ankylosing Spondylitis (MK-0663-163)

Condition:   Ankylosing Spondylitis
Intervention:  
Sponsor:   Merck Sharp & Dohme Corp.
Active, not recruiting - verified April 2014

BAY81-8781, I.V. Aspirin in the Indication of Acute Coronary Syndrome (ACS)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Acetylsalicylic acid (Aspirin, BAY 81-8781);   Drug: Acetylsalicylic acid (Aspirin, BAY 81-8781);   Drug: Acetylsalicylic acid (Aspirin, BAY 81-8781)
Sponsor:   Bayer
Recruiting - verified April 2014

Patient-Centered Adherence Intervention After Acute Coronary Syndrome (ACS) Hospitalization

Condition:   Acute Coronary Syndrome
Interventions:   Behavioral: Intervention;   Behavioral: Usual care
Sponsor:   Department of Veterans Affairs
Completed - verified April 2014

Sitagliptin Cardiovascular Outcome Study (MK-0431-082)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Sitagliptin phosphate;   Drug: Placebo
Sponsors:   Merck Sharp & Dohme Corp.;   Duke Clinical Research Institute, Oxford Diabetes Trials Unit
Active, not recruiting - verified April 2014

Collaborative Cardiac Care Project

Conditions:   Myocardial Ischemia;   Angina Pectoris;   Coronary Disease
Interventions:   Procedure: Collaborative care model;   Procedure: Group interventions;   Procedure: Facilitated consultation
Sponsor:   Department of Veterans Affairs
Completed - verified April 2014

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