Aortic Valve Stenosis

Clinical Trial Finder

Many patients with aortic valve stenosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Early Aortic Valve Lipoprotein(a) Lowering Trial

Condition:   Aortic Stenosis and Lipoprotein(a) Levels
Interventions:   Drug: Extended release Niacin;   Drug: Placebo Comparator
Sponsors:   McGill University Health Center;   George Thanassoulis;   Jewish General Hospital;   Laval University;   Quebec Heart Institute
Not yet recruiting - verified April 2014

Bicuspid Valve Aortopathy Feasibility Study

Condition:   Bicuspid Aortic Valve
Intervention:   Other: No interventions
Sponsors:   Oregon Health and Science University;   Emory University;   University of Colorado, Denver;   Baylor College of Medicine;   University of California, Los Angeles;   Penn State University
Recruiting - verified April 2014

HCMR - Novel Markers of Prognosis in Hypertrophic Cardiomyopathy

Condition:   Hypertrophic Cardiomyopathy
Intervention:   Other: None - this is an observational study
Sponsors:   University of Virginia;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified April 2014

Use of Cardiac-MRI to Predict Results for People With Severe Aortic Stenosis

Condition:   Aortic Valve Stenosis
Intervention:  
Sponsors:   National Institutes of Health Clinical Center (CC);   National Heart, Lung, and Blood Institute (NHLBI);   Medstar Washington Hospital Center
Withdrawn - verified April 2014

Valsartan for Attenuating Disease Evolution In Early Sarcomeric HCM

Condition:   Hypertrophic Cardiomyopathy
Interventions:   Drug: Valsartan;   Drug: Placebo
Sponsors:   New England Research Institutes;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified July 2013

Perceval S Aortic Heart Valve Study- North America

Conditions:   Aortic Valve Stenosis;   Aortic Valve Stenosis With Insufficiency;   Regurgitation, Aortic Valve;   Aortic Valve Incompetence
Intervention:   Device: Perceval S Aortic Heart Valve
Sponsor:   Sorin Group USA, Inc.
Recruiting - verified April 2014

Fetal Intervention for Aortic Stenosis and Evolving Hypoplastic Left Heart Syndrome

Conditions:   Aortic Stenosis;   Hypoplastic Left Heart Syndrome
Intervention:   Procedure: Fetal Aortic Valvuloplasty
Sponsor:   University of California, San Francisco
Recruiting - verified April 2014

Clinical Evaluation of MDT-2111 in Subjects With Small Aortic Annuli and Symptomatic Severe Aortic Stenosis

Condition:   Aortic Valve Stenosis
Intervention:   Device: MDT-2111 TAVI 23 mm
Sponsor:   Medtronic Cardiovascular
Active, not recruiting - verified April 2014

Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI).

Condition:   Severe Aortic Stenosis
Interventions:   Device: Medtronic CoreValve® System Transcatheter Aortic Valve Implantation (TAVI);   Procedure: Surgical Aortic Valve Replacement (SAVR)
Sponsor:   Medtronic Cardiovascular
Recruiting - verified April 2014

Safety and Effectiveness Study of Perceval S Valve for Extended CE Mark

Condition:   Aortic Valve Replacement
Intervention:   Device: Perceval S Valve Prosthesis
Sponsor:   Sorin Group
Active, not recruiting - verified April 2014

The PARTNER II Trial: Placement of AoRTic TraNscathetER Valves

Condition:   Symptomatic Severe Aortic Stenosis
Interventions:   Device: TAVR Implantation of the Transcatheter Aortic Valve Prosthesis;   Device: TAVR Implantation of the Transcatheter Aortic Valve Prosthesis;   Device: TAVR Implantation of the Transcatheter Aortic Valve Prosthesis;   Device: TAVR Implantation of the Transcatheter Aortic Valve Prosthesis;   Device: TAVR Implantation of the Transcatheter Aortic Valve Prosthesis;   Device: TAVR Implantation of the Transcatheter Aortic Valve Prosthesis
Sponsor:   Edwards Lifesciences
Recruiting - verified April 2014

Carpentier-Edwards PERIMOUNT Magna Ease Pericardial Bioprosthesis, Model 3300TFX

Conditions:   Coronary Artery Disease;   Aortic Valve Disorder;   Heart Failure;   Aortic Valve Stenosis;   Aortic Valve Insufficiency
Intervention:   Device: Implantation of CEP Magna Ease Model 3300TFX
Sponsor:   Edwards Lifesciences
Active, not recruiting - verified October 2012

Covered Cheatham Platinum CP Stents for the Prevention or Treatment of Aortic Wall Injury Associated With Coarctation of the Aorta

Condition:   Aortic Coarctation
Intervention:   Device: Cheatham Covered Platinum Stent
Sponsors:   Johns Hopkins University;   Richard E. Ringel;   Harvard University
Active, not recruiting - verified April 2014

The Perceived Impact of Children s Risk Status for Hypertrophic Cardiomyopathy on Families: an Exploratory Study

Condition:   Cardiovascular Disease
Intervention:  
Sponsors:   National Institutes of Health Clinical Center (CC);   National Human Genome Research Institute (NHGRI)
Completed - verified March 2014

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