Atherosclerosis

Clinical Trial Finder

Many patients with atherosclerosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Multicenter, Prospective, Randomized, Controlled, Double-blind Trial on the Impact of Rosuvastatin on Subclinical Markers of Atherosclerosis in Patients With Primary Necrotizing Vasculitides

Condition:   ANCA-associated Primary Necrotizing Vasculitides
Interventions:   Drug: Rosuvastatin;   Drug: Placebo
Sponsor:   Assistance Publique - Hôpitaux de Paris
Not yet recruiting - verified April 2014

Carnitine for the Treatment of Atherosclerosis.

Condition:   Metabolic Syndrome
Interventions:   Dietary Supplement: L-carnitine capsules;   Dietary Supplement: Lactose capsules
Sponsors:   Queen's University;   Heart and Stroke Foundation of Canada
Not yet recruiting - verified April 2014

Is There Room for Butter in a Healthy Diet?

Condition:   Atherosclerosis
Interventions:   Other: Danish butter;   Other: Olive oil
Sponsors:   University of Copenhagen;   The Danish Dairy Research Foundation, Denmark
Completed - verified April 2014

Study to Detect Biomarker Gradients in Coronary Arteries Using the Liquid Biopsy System

Condition:   Coronary Heart Disease
Intervention:  
Sponsors:   PlaqueTec Ltd;   Papworth Hospital NHS Foundation Trust
Not yet recruiting - verified April 2014

Atherosclerosis in High Risk Population Groups: An Assessment by Magnetic Resonance Imaging

Condition:   Atherosclerosis
Intervention:   Drug: Rosuvastatin 20 mg, Aspirin 81 mg
Sponsor:   Emory University
Active, not recruiting - verified April 2014

The IN.PACT SFA Clinical Study for the Treatment of Atherosclerotic Lesions in the Superficial Femoral Artery and/or Proximal Popliteal Artery Using the IN.PACT Admiral™ Drug-Eluting Balloon in a Chinese Patient Population

Condition:   Atherosclerosis
Intervention:   Device: IN.PACT Admiral Paclitaxel-Eluting Percutaneous Transluminal Angioplasty (PTA) Balloon Catheter
Sponsor:   Medtronic Endovascular
Recruiting - verified April 2014

Adenosine-induced Myocardial Blood Flow in Peripheral Artery Disease Patients

Conditions:   Peripheral Artery Disease;   Vascular Disease;   Arterial Occlusion Disease;   Intermittent Claudication;   Ankle Brachial Index (0.9 or Less)
Interventions:   Drug: Ticagrelor;   Drug: clopidogrel
Sponsor:   AstraZeneca
Not yet recruiting - verified April 2014

DIAMOND - Dual Antiplatelet Therapy to Reduce Myocardial Injury

Condition:   Coronary Artery Disease
Interventions:   Drug: Ticagrelor;   Drug: Placebo
Sponsors:   University of Edinburgh;   AstraZeneca
Not yet recruiting - verified April 2014

Post Market Surveillance Study of the Wingspan Stent System

Condition:   Intracranial Atherosclerosis
Intervention:   Device: Wingspan Stent System
Sponsor:   Stryker Neurovascular
Recruiting - verified April 2014

The Lipid-Rich Plaque Study

Conditions:   Coronary Artery Disease;   Atherosclerosis
Intervention:  
Sponsors:   InfraReDx;   Medstar Research Institute
Recruiting - verified April 2014

Comparison of the Ranger™ Paclitaxel-Coated PTA Balloon Catheter and Uncoated PTA Balloons in Femoropopliteal Arteries

Conditions:   Peripheral Artery Disease;   Claudication;   Atherosclerosis;   Arteriosclerosis
Interventions:   Device: Ranger DCB;   Device: uncoated PTA balloon
Sponsors:   Hemoteq AG;   Ceres GmbH evaluation & research;   CoreLab Bad Krozingen GmbH
Recruiting - verified April 2014

HsTnT in Stable Coronary Artery Disease

Condition:   Coronary Artery Disease
Intervention:   Other: Progress of CHD
Sponsors:   University Hospital Heidelberg;   AstraZeneca
Active, not recruiting - verified April 2014

The Relationship Between Aortic Pulse Wave and Peripheral Artery Occlusion Disease in Hemodialysis Patients

Conditions:   End-stage Renal Disease;   Hemodialysis;   Aortic Calcification;   Peripheral Artery Occlusion;   Cardiovascular Disease
Intervention:  
Sponsor:   National Taiwan University Hospital
Recruiting - verified April 2014

Correlation Between Coronary and Carotid Atherosclerotic Disease and Links With Clinical Outcomes

Condition:   Vascular Disease
Intervention:  
Sponsor:   Montreal Heart Institute
Recruiting - verified April 2014

Edoxaban in Peripheral Arterial Disease

Condition:   Peripheral Arterial Disease
Interventions:   Drug: edoxaban;   Drug: Clopidogrel;   Drug: Aspirin
Sponsors:   Daiichi Sankyo Inc.;   UMC Utrecht
Recruiting - verified April 2014

Iloprost Therapy in Patients With Critical Limb Ischemia

Condition:   Peripheral Arterial Disease
Intervention:   Drug: Iloprost (Ilomedin, BAYQ6256)
Sponsor:   Bayer
Recruiting - verified April 2014

Evaluation of Efficacy of the EPIC™ Self-Expanding Nitinol Vascular Stent

Conditions:   Peripheral Arterial Diseases;   Superficial Femoral Artery Stenosis
Intervention:   Device: EPIC™ Self-Expanding Nitinol Vascular Stent
Sponsors:   Provascular GmbH;   Boston Scientific Corporation
Completed - verified April 2014

REVEAL: Randomized EValuation of the Effects of Anacetrapib Through Lipid-modification

Condition:   Atherosclerotic Cardiovascular Disease
Interventions:   Drug: anacetrapib;   Drug: placebo anacetrapib
Sponsors:   University of Oxford;   Merck Sharp & Dohme Corp.
Active, not recruiting - verified April 2014

Bone Marrow Aspirate Concentrate (BMAC) for Treatment of Critical Limb Ischemia (CLI)

Condition:   Critical Limb Ischemia
Interventions:   Device: BMAC injection;   Device: Placebo injection
Sponsor:   Harvest Technologies
Recruiting - verified April 2014

The Evicel Post-Authorization Surveillance Study

Conditions:   Peripheral Vascular Disease;   Hemorrhage
Intervention:   Biological: EVICEL ™ Fibrin Sealant (Human)
Sponsors:   Ethicon, Inc.;   OMRIX Biopharmaceuticals
Active, not recruiting - verified April 2014

Study of the Effect of Innate on the Inflammatory Response to Endotoxin

Conditions:   Asthma;   Atherosclerosis;   Metabolic Syndrome;   Insulin Resistance;   Cancer
Intervention:  
Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute of Environmental Health Sciences (NIEHS)
Recruiting - verified February 2014

AFRICA: Atorvastatin Plus Fenofibric Acid (TriLipix) in the Reduction of Intermediate Coronary Atherosclerosis

Condition:   Coronary Atherosclerosis
Interventions:   Drug: Placebo;   Drug: TriLipix
Sponsor:   Piedmont Healthcare
Terminated - verified April 2014

Individualized Comprehensive Atherosclerosis Risk-reduction Evaluation Program

Condition:   Atherosclerosis
Intervention:  
Sponsors:   Piedmont Healthcare;   Abbott
Recruiting - verified April 2014

Detection of Subclinical Atherosclerosis in Asymptomatic Individuals

Condition:   Coronary Artery Disease
Intervention:   Procedure: Cardiac CT
Sponsor:   Piedmont Healthcare
Recruiting - verified April 2014

Atherosclerotic Plaque Characterization

Condition:   Atherosclerosis
Intervention:  
Sponsor:   Piedmont Healthcare
Completed - verified April 2014

Strategies to Maintain Cardiac Risk Control After Discharge From Cardiovascular Risk Reduction Clinic

Conditions:   Diabetes;   Dyslipidemia;   Hypertension;   Coronary Atherosclerosis
Interventions:   Behavioral: Counseling;   Behavioral: Interactive Education;   Behavioral: Group Support;   Procedure: Pharmacologic case management
Sponsors:   Providence VA Medical Center;   Merck Sharp & Dohme Corp.
Completed - verified April 2014

Causes and Natural History of Dyslipidemias

Condition:   Dyslipidemias
Intervention:  
Sponsors:   National Institutes of Health Clinical Center (CC);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified April 2014

Salsalate Therapy to Reduce Insulin Resistance and Cardiovascular Risk

Conditions:   Atherosclerosis;   Cardiovascular Disease;   Inflammation;   Insulin Resistance;   Noninsulin-dependent Diabetes Mellitus
Interventions:   Drug: Salsalate;   Drug: Placebo
Sponsors:   Department of Veterans Affairs;   Joslin Diabetes Center
Completed - verified April 2014

Evaluation of Lipoproteins

Conditions:   Hyperlipidemia;   Hyperlipoproteinemia;   Hypolipoproteinemia
Intervention:  
Sponsors:   National Institutes of Health Clinical Center (CC);   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified April 2014

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