Atherosclerosis

Clinical Trial Finder

Many patients with atherosclerosis are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Atherosclerosis in High Risk Population Groups: An Assessment by Magnetic Resonance Imaging

Condition:   Atherosclerosis
Intervention:   Drug: Rosuvastatin 20 mg, Aspirin 81 mg
Sponsor:   Emory University
Active, not recruiting - verified April 2014

Progression of Coronary Atherosclerosis in Asymptomatic Diabetic Subjects

Conditions:   Type 2 Diabetes;   Coronary Artery Disease
Intervention:  
Sponsors:   British Cardiac Research Trust;   Royal Free Hospital NHS Foundation Trust;   North West London Hospitals NHS Trust;   Barnet and Chase Farm Hospitals NHS Trust;   Diabetes and Obesity Research Network;   Lund University;   Health Diagnostic Laboratory, Inc.
Recruiting - verified April 2014

DIAMOND - Dual Antiplatelet Therapy to Reduce Myocardial Injury

Condition:   Coronary Artery Disease
Interventions:   Drug: Ticagrelor;   Drug: Placebo
Sponsors:   University of Edinburgh;   AstraZeneca
Not yet recruiting - verified April 2014

EARly Prevention of aTHeroma Progression

Condition:   Coronary Arteriosclerosis
Interventions:   Behavioral: Standard Therapy;   Drug: Rosuvastatin
Sponsors:   Asan Medical Center;   CHEOL WHAN LEE, M.D., Ph.D;   AstraZeneca
Not yet recruiting - verified April 2014

The Impact of Ezetimibe on Biochemical Markers of Cardiovascular Risk in Kidney Transplant Patients

Conditions:   Dyslipidemia;   Transplants
Intervention:   Drug: Ezetimibe
Sponsor:   University Medical Centre Ljubljana
Not yet recruiting - verified April 2014

CVI Drug Coated Balloon First In Human Trial

Condition:   Peripheral Arterial Disease
Intervention:   Device: Percutaneous Transluminal Angioplasty
Sponsor:   Covidien
Active, not recruiting - verified April 2014

Comprehensive Lifestyle Modification for Patients With Hypertension and Metabolic Syndrome: a Multicenter Randomized Controlled Trial

Conditions:   Hypertension;   Metabolic Syndrome
Interventions:   Behavioral: Comprehensive Lifestyle Modification;   Behavioral: DASH
Sponsors:   Universität Duisburg-Essen;   Kliniken Essen-Mitte;   Immanuel Hospital Berlin, Berlin, Germany;   Charité University Medical Center, Berlin, Germany;   University of Witten/Herdecke
Recruiting - verified April 2014

Exercise Therapy With Risk Factor Management and Life Style Coaching After Vascular Intervention for Patients With Peripheral Arterial Disease

Condition:   Peripheral Arterial Disease, Rutherford Stage 4 and 5 With the Possibility to Improve Vascularization.
Intervention:   Behavioral: Supervised Exercise Therapy
Sponsor:   Catharina Ziekenhuis Eindhoven
Recruiting - verified April 2014

The Effect of Pomegranate Juice (PJ) on Oxidative Stress Biomarkers During Treatment With IV Iron During One Dialysis Session

Condition:   Cardiovascular Disease (CVD)
Interventions:   Dietary Supplement: PJ;   Drug: IV iron
Sponsors:   Western Galilee Hospital-Nahariya;   Luoxis
Not yet recruiting - verified April 2014

Platelet Activity in Vascular Surgery and Cardiovascular Events

Conditions:   Cardiovascular Disease;   Peripheral Artery Disease
Intervention:  
Sponsors:   New York University School of Medicine;   National Institutes of Health (NIH)
Recruiting - verified April 2014

Physical Activity Daily - An Internet-Based Walking Program for Patients With Peripheral Arterial Disease

Condition:   Peripheral Arterial Disease
Interventions:   Behavioral: Supervised PAD rehab;   Behavioral: Internet-based walking program
Sponsors:   University of Michigan;   National Institute on Aging (NIA)
Not yet recruiting - verified April 2014

HsTnT in Stable Coronary Artery Disease

Condition:   Coronary Artery Disease
Intervention:   Other: Progress of CHD
Sponsors:   University Hospital Heidelberg;   AstraZeneca
Active, not recruiting - verified April 2014

The Relationship Between Aortic Pulse Wave and Peripheral Artery Occlusion Disease in Hemodialysis Patients

Conditions:   End-stage Renal Disease;   Hemodialysis;   Aortic Calcification;   Peripheral Artery Occlusion;   Cardiovascular Disease
Intervention:  
Sponsor:   National Taiwan University Hospital
Recruiting - verified April 2014

Safety Trial Of CTX Cells In Patients With Lower Limb Ischaemia

Condition:   Peripheral Arterial Disease
Intervention:   Biological: CTX DP
Sponsor:   ReNeuron Limited
Recruiting - verified April 2014

Correlation Between Coronary and Carotid Atherosclerotic Disease and Links With Clinical Outcomes

Condition:   Vascular Disease
Intervention:  
Sponsor:   Montreal Heart Institute
Recruiting - verified April 2014

Study of Human Placenta-derived Cells (PDA002) to Evaluate the Safety and Effectiveness in Subjects With PAD and DFU

Conditions:   Peripheral Arterial Disease;   Diabetic Foot
Interventions:   Biological: 3 x 10^6 cells;   Biological: 10 x 10^6 cells;   Biological: 30 x 10^6 cells;   Biological: 100 x 10^6 cells
Sponsor:   Celgene Corporation
Recruiting - verified April 2014

Edoxaban in Peripheral Arterial Disease

Condition:   Peripheral Arterial Disease
Interventions:   Drug: edoxaban;   Drug: Clopidogrel;   Drug: Aspirin
Sponsors:   Daiichi Sankyo Inc.;   UMC Utrecht
Recruiting - verified April 2014

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

Condition:   Prevention & Control
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin;   Drug: Aspirin placebo;   Drug: Rivaroxaban placebo;   Drug: Pantoprazole
Sponsors:   Bayer;   Hamilton Health Sciences Corporation, Population Health Research Institute
Recruiting - verified April 2014

Revacept in Symptomatic Carotid Stenosis (Revacept/CS/02)

Conditions:   Carotid Stenosis;   Atherosclerosis;   Stroke;   Transient-ischaemic Attack;   TIA;   Amaurosis Fugax
Interventions:   Drug: Revacept;   Drug: Placebo
Sponsor:   AdvanceCor GmbH
Recruiting - verified April 2014

Estimation of the Long Term Effectiveness of Routine Use of Cardiac Shock Wave Therapy

Condition:   Coronary Heart Disease (CHD)
Interventions:   Other: Treatment of CHD risk factors;   Drug: Aspirin, Isosorbide mononitrate, Atenolol, Enalapril.;   Drug: Aspirin, Isosorbide mononitrate, Atenolol, Enalapril.;   Procedure: PCA;   Procedure: CABG;   Device: Cardiospec;   Drug: Aspirin, Isosorbide mononitrate, Atenolol, Enalapril
Sponsor:   City Hospital No 40, Saint Petersburg, Russia
Withdrawn - verified April 2014

Risk Factor Analysis for Developing Metabolic Syndrome in Korean Adults

Condition:   Metabolic Syndrome, Atherosclerosis
Intervention:  
Sponsor:   Korea University
Recruiting - verified April 2014

A Study of Dalcetrapib in Patients With Stable Coronary Heart Disease, With Coronary Heart Disease Risk Equivalents or at Elevated Risk for Cardiovascular Disease

Condition:   Cardiovascular Disease, Coronary Heart Disease, Dyslipidemia, Peripheral Arterial Disease (PAD)
Interventions:   Drug: dalcetrapib;   Drug: Placebo;   Other: Background care
Sponsor:   Hoffmann-La Roche
Completed - verified April 2014

Investigation of the Effect of Dietary Nitrate Treatment on Endothelial Function and Platelet Reactivity in Hypercholesterolemics.

Condition:   Hypercholesterolemia
Intervention:   Dietary Supplement: beetroot juice
Sponsors:   Queen Mary University of London;   British Heart Foundation
Completed - verified April 2014

Iloprost Therapy in Patients With Critical Limb Ischemia

Condition:   Peripheral Arterial Disease
Intervention:   Drug: Iloprost (Ilomedin, BAYQ6256)
Sponsor:   Bayer
Recruiting - verified April 2014

Correlation Between Coronary and Carotid Atherosclerotic Disease (CAD) and Links With Clinical Outcomes

Condition:   Atherosclerosis
Intervention:  
Sponsors:   Canadian Atherosclerosis Imaging Network;   Canadian Institutes of Health Research (CIHR)
Recruiting - verified April 2014

Carotid Plaque Imaging in Acute Stroke

Conditions:   Stroke;   Ischemic Attack, Transient
Intervention:  
Sponsors:   Ludwig-Maximilians - University of Munich;   Technische Universität München
Recruiting - verified April 2014

The Jetstream G3™ Calcium Study

Condition:   Peripheral Arterial Disease
Intervention:   Device: Jetstream
Sponsor:   MEDRAD, Inc.
Completed - verified April 2014

Bone Marrow Aspirate Concentrate (BMAC) for Treatment of Critical Limb Ischemia (CLI)

Condition:   Critical Limb Ischemia
Interventions:   Device: BMAC injection;   Device: Placebo injection
Sponsor:   Harvest Technologies
Recruiting - verified April 2014

AFRICA: Atorvastatin Plus Fenofibric Acid (TriLipix) in the Reduction of Intermediate Coronary Atherosclerosis

Condition:   Coronary Atherosclerosis
Interventions:   Drug: Placebo;   Drug: TriLipix
Sponsor:   Piedmont Healthcare
Terminated - verified April 2014

Individualized Comprehensive Atherosclerosis Risk-reduction Evaluation Program

Condition:   Atherosclerosis
Intervention:  
Sponsors:   Piedmont Healthcare;   Abbott
Recruiting - verified April 2014

Detection of Subclinical Atherosclerosis in Asymptomatic Individuals

Condition:   Coronary Artery Disease
Intervention:   Procedure: Cardiac CT
Sponsor:   Piedmont Healthcare
Recruiting - verified April 2014

Atherosclerotic Plaque Characterization

Condition:   Atherosclerosis
Intervention:  
Sponsor:   Piedmont Healthcare
Completed - verified April 2014

A Multiple Ascending Dose Study of RO4905417 in Healthy Volunteers and Patients With Peripheral Arterial Disease (PAD).

Condition:   Peripheral Arterial Disease (PAD)
Interventions:   Drug: RO4905417;   Drug: placebo;   Drug: RO4905417;   Drug: placebo;   Drug: RO4905417;   Drug: placebo
Sponsor:   Hoffmann-La Roche
Completed - verified April 2014

Magnetic Resonance Imaging to Identify Characteristics of Plaque Build-Up in People With Peripheral Arterial Disease

Condition:   Peripheral Vascular Diseases
Intervention:  
Sponsors:   Northwestern University;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified April 2014

FGF-1 for Intramuscular Injection for the Treatment of Peripheral Arterial Disease

Conditions:   Peripheral Arterial Disease;   Stenosis;   Intermittent Claudication
Intervention:   Drug: FGF-1
Sponsor:   CardioVascular BioTherapeutics, Inc.
Not yet recruiting - verified August 2013

Strategies to Maintain Cardiac Risk Control After Discharge From Cardiovascular Risk Reduction Clinic

Conditions:   Diabetes;   Dyslipidemia;   Hypertension;   Coronary Atherosclerosis
Interventions:   Behavioral: Counseling;   Behavioral: Interactive Education;   Behavioral: Group Support;   Procedure: Pharmacologic case management
Sponsors:   Providence VA Medical Center;   Merck Sharp & Dohme Corp.
Completed - verified April 2014

Reducing Risk Factors in Peripheral Arterial Disease

Conditions:   Cardiovascular Diseases;   Peripheral Vascular Diseases
Intervention:   Behavioral: Health-Counselor Mediated Telephone Counseling Intervention
Sponsors:   Northwestern University;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified April 2014

Cardiovascular Evaluation of Patients With High Cholesterol and Normal Volunteers

Conditions:   Atherosclerosis;   Hypercholesterolemia
Intervention:  
Sponsors:   National Institutes of Health Clinical Center (CC);   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified March 2014

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