Atrial Fibrillation Also called: AF, Afib

Clinical Trial Finder

Many patients with atrial fibrillation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Treatment of Atrial Fibrillation in Patients by Pulmonary Vein Isolation, Renal Artery Denervation or Both.

Conditions:   Paroxysmal Atrial Fibrillation;   Persistent Atrial Fibrillation;   Hypertension
Intervention:   Procedure: procedure
Sponsor:   Diagram B.V.
Recruiting - verified April 2014

Acupuncture in Persistent Atrial Fibrillation

Condition:   Persistent Atrial Fibrillation
Interventions:   Procedure: Active Acupuncture;   Procedure: Sham acupuncture;   Drug: flecainide
Sponsors:   Kyunghee University Medical Center;   Ministry of Health & Welfare, Korea
Recruiting - verified April 2014

ECG Derived Respiration for Automated Screening of Sleep Disordered Breathing in Chronic Heart Failure Patients

Conditions:   Heart Failure;   Sleep Apnea Syndromes;   Polysomnography
Intervention:   Device: ventilatory polygraphic recordings
Sponsor:   Centre Hospitalier Universitaire de Saint Etienne
Enrolling by invitation - verified April 2014

CArdioversion of Short Duration Atrial Fibrillation

Conditions:   Atrial Fibrillation;   Electrocardiography;   Electrical Remodeling
Intervention:  
Sponsor:   Region Skane
Recruiting - verified March 2014

NON INVASIVE MAPPING OF ATRIAL FIBRILLATION

Condition:   Atrial Fibrillation
Intervention:  
Sponsors:   Brugmann University Hospital;   Centre Hospitalier Universitaire Brugmann
Recruiting - verified April 2014

Vasoactive Drugs in Intensive Care Unit

Condition:   Shock
Interventions:   Drug: Norepinephrine;   Drug: Epinephrine;   Drug: Phenylephrine;   Drug: Vasopressin
Sponsor:   University of Chicago
Not yet recruiting - verified April 2014

BAY 59-7939 (Xarelto, SPAF), Non Interventional Studies

Condition:   Atrial Fibrillation
Interventions:   Drug: Phenprocoumon (Marcumar);   Drug: Rivaroxaban (Xarelto, BAY-59 7939)
Sponsor:   Bayer
Recruiting - verified April 2014

Therapeutic Equivalence Between Branded and Generic Warfarin Tablets in Brazil

Condition:   Atrial Fibrillation
Interventions:   Drug: Marevan®;   Drug: generic warfarin #1;   Drug: generic warfarin #2
Sponsor:   Federal University of São Paulo
Not yet recruiting - verified April 2014

Stroke Feasibility Study

Conditions:   Atrial Fibrillation;   AFib
Intervention:   Device: AtriClip LAA Exclusion Device
Sponsor:   AtriCure, Inc.
Recruiting - verified April 2014

Genetically Targeted Therapy for the Prevention of Symptomatic Atrial Fibrillation in Patients With Heart Failure

Conditions:   Atrial Fibrillation;   Atrial Flutter
Interventions:   Drug: bucindolol hydrochloride;   Drug: metoprolol succinate
Sponsors:   ARCA Biopharma, Inc.;   Medtronic
Recruiting - verified April 2014

GLORIA-AF Registry Program (Phase II/III)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified April 2014

HCMR - Novel Markers of Prognosis in Hypertrophic Cardiomyopathy

Condition:   Hypertrophic Cardiomyopathy
Intervention:   Other: None - this is an observational study
Sponsors:   University of Virginia;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified April 2014

Pradaxa Study in Non-valvular Atrial Fibrillation Patients With Severely Impaired Renal Function

Condition:   Atrial Fibrillation
Intervention:   Drug: Pradaxa, dabigatran etexilate
Sponsor:   Boehringer Ingelheim
Recruiting - verified April 2014

Impact of the Pulmonary Vein Isolation on Exercise Capacity in Patients With Chronic Atrial Fibrillation

Condition:   Chronic Atrial Fibrillation
Intervention:   Procedure: Radiofrequency catheter ablation
Sponsors:   Texas Cardiac Arrhythmia Research Foundation;   University of Texas at Austin
Recruiting - verified April 2014

Exploring the Efficacy of Once Daily Oral Rivaroxaban for Treatment of Thrombus in Left Atrial/Left Atrial Appendage in Subjects With Nonvalvular Atrial Fibrillation or Atrial Flutter

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsors:   Bayer;   Janssen Research & Development, LLC
Recruiting - verified April 2014

DF4 Master Study (Safety and Efficacy Study)

Conditions:   Ventricular Tachycardia;   Ventricular Fibrillation;   Sudden Cardiac Death;   Heart Failure
Intervention:   Device: Iforia/Ilesto ICD/CRT-D, Linox smart DF4 lead/ Protego
Sponsor:   Biotronik SE & Co. KG
Active, not recruiting - verified April 2014

Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation in Asia

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsor:   Bayer
Recruiting - verified April 2014

A Study Exploring Two Treatment Strategies in Patients With Atrial Fibrillation Who Undergo Catheter Ablation Therapy

Condition:   Atrial Fibrillation
Interventions:   Drug: rivaroxaban;   Drug: uninterrupted vitamin K antagonist (VKA)
Sponsor:   Janssen Scientific Affairs, LLC
Recruiting - verified April 2014

Clinical Outcome of Pacemaker paTIents According to Pacing Modality and Primary INDications OPTI-MIND 2

Condition:   Bradyarrhythmia
Intervention:  
Sponsor:   Guidant Corporation
Recruiting - verified April 2014

Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II (ORBIT-AF II)

Condition:   Atrial Fibrillation
Intervention:   Other: Patients with Atrial Fibrillation
Sponsors:   Janssen Scientific Affairs, LLC;   Duke Clinical Research Institute
Recruiting - verified April 2014

Effect of 3 Years of Exercise on Development of Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Behavioral: High intensity exercise;   Behavioral: Moderate intensity exercise;   Behavioral: Control
Sponsors:   Norwegian University of Science and Technology;   St. Olavs Hospital
Recruiting - verified April 2014

GLORIA-AF Registry Program (Phase II/III - EU/EEA Member States)

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified April 2014

Outcome of Atrial Fibrillation Ablation After Permanent Pulmonary Vein Antrum Isolation With or Without Proven Left Atrial Posterior Wall Isolation

Condition:   Atrial Fibrillation
Interventions:   Procedure: Pulmonary vein antrum isolation (PVAI);   Procedure: PVAI plus left atrial posterior wall (LAPW) isolation
Sponsors:   Texas Cardiac Arrhythmia Research Foundation;   Centro Cardiologico Monzino, IRCCS, Milan, Italy;   Catholic University of the Sacred Heart;   Capital Medical University;   Tong-Ji Hospital, Tong-Ji Medical College, HUST, Wuhan, China
Recruiting - verified April 2014

Improving Anticoagulation Control in VISN 1

Conditions:   Anticoagulants;   Atrial Fibrillation;   Venous Thromboembolism
Intervention:   Behavioral: Outreach, Education, and Motivational Interviewing
Sponsor:   Department of Veterans Affairs
Not yet recruiting - verified April 2014

Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:   Drug: Rivaroxaban (Xarelto, BAY59-7939)
Sponsor:   Bayer
Active, not recruiting - verified April 2014

Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI).

Condition:   Severe Aortic Stenosis
Interventions:   Device: Medtronic CoreValve® System Transcatheter Aortic Valve Implantation (TAVI);   Procedure: Surgical Aortic Valve Replacement (SAVR)
Sponsor:   Medtronic Cardiovascular
Recruiting - verified April 2014

Recording for Potential AF Drivers and Patient Specific Atrial Anatomy & Atrial Electrogram Maps

Condition:   Atrial Fibrillation
Intervention:   Procedure: 64 pole basket catheter
Sponsor:   Virginia Commonwealth University
Completed - verified April 2014

Atrial Fibrillation Progression Trial

Condition:   Atrial Fibrillation
Interventions:   Device: Left Atrial Ablation (Carto® 3, Carto® XP System, or Carto® RMT and ThermoCool®);   Drug: Rate or Rhythm Control Therapy
Sponsor:   Biosense Webster, Inc.
Recruiting - verified April 2014

UMBRELLA - Incidence of Arrhythmias in Spanish Population With a Medtronic Implantable Cardiac Defibrillator Implant

Conditions:   Cardiomyopathies;   Cardiac Arrhythmias;   Cardiac Arrest
Intervention:  
Sponsor:   Medtronic Bakken Research Center
Recruiting - verified April 2014

A Study to Evaluate the Effect of Ranolazine and Dronedarone When Given Alone and in Combination in Patients With Paroxysmal Atrial Fibrillation (HARMONY)

Condition:   Atrial Fibrillation
Interventions:   Drug: Placebo;   Drug: Ranolazine;   Drug: Dronedarone;   Drug: Ranolazine and Dronedarone low dose 1;   Drug: Ranolazine and Dronedarone low dose 2
Sponsor:   Gilead Sciences
Completed - verified April 2014

A Prospective, Open Label Study Evaluating Two Management Strategies on Gastrointestinal Symptoms in Patients Newly on Treatment With Pradaxa for the Prevention of Stroke and Systemic Embolism With Non-valvular Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Drug: pantoprazole;   Drug: Pradaxa (dabigatran etexilate);   Drug: Pradaxa, within 30 minutes after a meal;   Drug: Pradaxa (dabigatran etexilate)
Sponsor:   Boehringer Ingelheim
Recruiting - verified April 2014

GLORIA-AF Registry Program - Second and Third Phases

Conditions:   Stroke;   Atrial Fibrillation
Intervention:  
Sponsor:   Boehringer Ingelheim
Recruiting - verified April 2014

Effect of Catheter Ablation on Clinical Course of Migraine in AF Patients With or Without Previous History of Migraine

Conditions:   Migraine;   Atrial Fibrillation
Interventions:   Procedure: Radiofrequency catheter ablation;   Procedure: Radiofrequency catheter ablation
Sponsor:   Texas Cardiac Arrhythmia Research Foundation
Active, not recruiting - verified August 2013

Anticoagulation in Stent Intervention

Conditions:   Atrial Fibrillation;   Stroke
Interventions:   Drug: Acetylsalicylic Acid + clopidogrel + acenocoumarol;   Drug: Acetylsalicylic Acid + clopidogrel
Sponsor:   Hospital Universitari Vall d'Hebron Research Institute
Recruiting - verified April 2014

Safety and Effectiveness of Oral Alendronate Therapy on Bone Mineral Density in HIV-infected Children and Adolescents With Low Bone Mineral Density

Condition:   HIV Infections
Interventions:   Drug: Alendronate;   Drug: Alendronate placebo;   Dietary Supplement: Calcium carbonate/vitamin D
Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Active, not recruiting - verified April 2014

Global Study to Assess the Safety and Effectiveness of Edoxaban (DU-176b) vs Standard Practice of Dosing With Warfarin in Patients With Atrial Fibrillation

Conditions:   Stroke;   Atrial Fibrillation;   Embolism
Interventions:   Drug: warfarin tablets;   Drug: Edoxaban tablets (high dose regimen);   Drug: Edoxaban tablets (low dose regimen)
Sponsors:   Daiichi Sankyo Inc.;   The TIMI Study Group
Completed - verified April 2014

Short Term Outcomes From Minimally Invasive Surgery for the Treatment of Atrial Fibrillation

Condition:   Atrial Fibrillation
Intervention:  
Sponsor:   Virginia Commonwealth University
Completed - verified April 2014

Evaluating the Relationship Between Fatty Acids and Heart Disease

Conditions:   Cardiovascular Diseases;   Heart Failure, Congestive;   Atrial Fibrillation;   Cerebrovascular Accident
Intervention:  
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI);   Office of Dietary Supplements (ODS)
Completed - verified April 2014

Boston Area Anticoagulation Trial for Atrial Fibrillation (BAATAF)

Conditions:   Arrhythmia;   Atrial Fibrillation;   Cardiovascular Diseases;   Cerebral Embolism and Thrombosis;   Cerebrovascular Disorders;   Heart Diseases;   Thrombophlebitis;   Cerebrovascular Accident
Intervention:   Drug: warfarin
Sponsors:   Massachusetts General Hospital;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified April 2014

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