Coronary Artery Disease

Clinical Trial Finder

Many patients with coronary artery disease are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Rubidium Elution System Performance Testing

Condition:   Coronary Artery Disease
Intervention:  
Sponsors:   University of Ottawa Heart Institute;   Jubilant DraxImage Inc.
Recruiting - verified April 2014

Mi-RNAs and Specificity of Hs-TnT in Symptomatic ED Patients

Conditions:   Coronary Artery Disease;   Myocardial Infarction
Intervention:  
Sponsors:   University Hospital Heidelberg;   German Heart Research Foundation
Not yet recruiting - verified April 2014

Progression of Coronary Atherosclerosis in Asymptomatic Diabetic Subjects

Conditions:   Type 2 Diabetes;   Coronary Artery Disease
Intervention:  
Sponsors:   British Cardiac Research Trust;   Royal Free Hospital NHS Foundation Trust;   North West London Hospitals NHS Trust;   Barnet and Chase Farm Hospitals NHS Trust;   Diabetes and Obesity Research Network;   Lund University;   Health Diagnostic Laboratory, Inc.
Recruiting - verified April 2014

DIAMOND - Dual Antiplatelet Therapy to Reduce Myocardial Injury

Condition:   Coronary Artery Disease
Interventions:   Drug: Ticagrelor;   Drug: Placebo
Sponsors:   University of Edinburgh;   AstraZeneca
Not yet recruiting - verified April 2014

EARly Prevention of aTHeroma Progression

Condition:   Coronary Arteriosclerosis
Interventions:   Behavioral: Standard Therapy;   Drug: Rosuvastatin
Sponsors:   Asan Medical Center;   CHEOL WHAN LEE, M.D., Ph.D;   AstraZeneca
Not yet recruiting - verified April 2014

Evaluation of a New Design of Crowns in the Posterior Teeth

Conditions:   Broken Down Molars;   IPS-emmax Crowns
Intervention:   Other: IPS.emmax endocrown
Sponsor:   Damascus University
Not yet recruiting - verified March 2014

Characterization of Changes in Ventricular Mechanics in Response to Lexiscan Stress Using Tagged Cine Cardiac Magnetic Resonance Imaging

Condition:   Coronary Artery Disease
Intervention:   Drug: Regadenoson
Sponsors:   Aspire Foundation;   Timothy M. Bateman;   Saint Luke's Health System;   Saint Luke's Cardiovascular Consultants
Not yet recruiting - verified April 2014

Copeptin Testing During Pre-hospital Care in the Treatment of Chest Pain Suggestive of Acute Coronary Syndrome

Condition:   Chest Pain
Interventions:   Biological: Blood work in the ambulance;   Biological: Blood work upon arrival in the emergency room;   Biological: Blood work at 3 hours post-arrival in the emergency room
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Not yet recruiting - verified April 2014

Prognostic Value of Biomarkers Associated With Endothelial Progenitor Cells Mobilization in Acute Coronary Syndromes

Condition:   Acute Coronary Syndromes
Intervention:   Other: blood sample
Sponsor:   Assistance Publique Hopitaux De Marseille
Not yet recruiting - verified April 2014

The ImPact of Trimetazidine on MicrOcirculation After Stenting for Stable Coronary Artery Disease

Conditions:   Coronary Artery Disease;   Microcirculation;   Vascular Resistance
Intervention:   Drug: trimetazidine
Sponsor:   Clinical Hospital Center Zemun
Recruiting - verified April 2014

Aerobic Exercise on Ventilatory Efficiency in CAD Patients

Conditions:   Coronary Artery Disease;   Exercise Addiction;   Complication, Cardio-respiratory
Intervention:   Other: Aerobic exercise training
Sponsor:   Hospital TotalCor
Completed - verified April 2014

Improving Adherence to Medication After Coronary Artery Bypass Surgery (CABG) in Older Adults

Condition:   Coronary Artery Bypass Grafting (CABG) Surgery
Interventions:   Behavioral: Motivational Interviewing (MI;   Behavioral: volitional intervention;   Behavioral: Routine discharge counseling
Sponsor:   Qazvin University Of Medical Sciences
Recruiting - verified April 2014

Effects of Beta-blockade on Cardiopulmonary Exercise Testing

Condition:   Abdominal Aortic Aneurysm Patients Under Surveillance
Intervention:   Drug: Bisoprolol
Sponsors:   Aintree University Hospitals NHS Foundation Trust;   Michelle Mossa
Completed - verified April 2014

BioMime Vs. Xience Randomised Control Clinical Study

Condition:   Coronary Artery Disease
Interventions:   Device: Sirolimus Eluting Coronary Stent;   Device: Everolimus-eluting Coronary stent
Sponsor:   Meril Life Sciences Pvt. Ltd.
Not yet recruiting - verified April 2014

A Comparison of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention and Coronary Artery Bypass Graft Surgery in Patients With Multivessel Coronary Artery Disease

Conditions:   Coronary Disease;   Coronary Stenosis
Interventions:   Procedure: FFR guided PCI;   Procedure: CABG
Sponsors:   Stanford University;   Cardiovascular Center Aalst, Belgium;   Catharina Hospital Eindhoven;   Golden Jubilee National Hospital;   University of California, Irvine;   Medtronic;   St. Jude Medical;   Genae
Not yet recruiting - verified April 2014

A Comparison of the Effects of Ketamine and Remifentanil on Serum Cystatin-c Levels in CABG Surgery

Condition:   Coronary Artery Disease
Interventions:   Drug: remifentanil;   Drug: Ketamine
Sponsor:   Turkiye Yuksek Ihtisas Education and Research Hospital
Completed - verified April 2014

Comprehensive Lifestyle Modification for Patients With Hypertension and Metabolic Syndrome: a Multicenter Randomized Controlled Trial

Conditions:   Hypertension;   Metabolic Syndrome
Interventions:   Behavioral: Comprehensive Lifestyle Modification;   Behavioral: DASH
Sponsors:   Universität Duisburg-Essen;   Kliniken Essen-Mitte;   Immanuel Hospital Berlin, Berlin, Germany;   Charité University Medical Center, Berlin, Germany;   University of Witten/Herdecke
Recruiting - verified April 2014

PATient Navigator to rEduce Readmissions

Conditions:   Chronic Obstructive Pulmonary Disease;   Heart Failure;   Sickle Cell Disease;   Myocardial Infarction;   Pneumonia;   Vascular Procedures
Interventions:   Behavioral: Hospital usual care;   Behavioral: Patient Navigator;   Behavioral: Peer-led telephone support line
Sponsors:   University of Illinois at Chicago;   Patient-Centered Outcomes Research Institute (PCORI);   University of Illinois at Urbana-Champaign;   Society of Hospital Medicine;   COPD Foundation;   University of Kentucky;   Mended Hearts;   American Heart Association;   Sickle Cell Disease Association of Illinois;   AcademyHealth;   The National Association of Social Workers Foundation;   Respiratory Health Association of Metropolitan Chicago;   University of Illinois Sickle Cell Patient Council;   National Jewish Health;   Olmsted Medical Center;   Baystate Medical Center;   Department of Veterans Affairs
Not yet recruiting - verified April 2014

A Phase 2b Study of CSL112 in Subjects With Acute Myocardial Infarction.

Condition:   Acute Myocardial Infarction
Interventions:   Biological: CSL112;   Biological: Placebo
Sponsor:   CSL Behring
Not yet recruiting - verified April 2014

Correlation Between Reticulated Platelets and Major Adverse Cardiac and Cerebrovascular Events After Noncardiac Surgery

Conditions:   Cardiac Death;   Congestive Heart Failure;   Angina Pectoris;   Stroke;   Pulmonary Embolism;   Deep Vein Thrombosis
Intervention:  
Sponsor:   Technische Universität München
Recruiting - verified April 2014

Computed Tomography and Biomarker Analysis in Diagnosing Coronary Artery Disease in Asymptomatic Patients Who Have Undergone Stem Cell Transplant

Conditions:   Cancer Survivor;   Diabetes Mellitus;   Hypertension
Interventions:   Procedure: computed tomography;   Other: cytology specimen collection procedure;   Other: laboratory biomarker analysis;   Other: questionnaire administration
Sponsors:   City of Hope Medical Center;   National Cancer Institute (NCI)
Recruiting - verified April 2014

Antiplatelet Therapy Following Stent Implantation

Conditions:   Acute Myocardial Infarction;   Coronary Syndrome;   Angina, Unstable
Intervention:  
Sponsor:   Elpen Pharmaceutical Co. Inc.
Recruiting - verified January 2014

The Lipid-Rich Plaque Study

Conditions:   Coronary Artery Disease;   Atherosclerosis
Intervention:  
Sponsors:   InfraReDx;   Medstar Research Institute
Recruiting - verified April 2014

BIOFLOW III Satellite-ELADIS

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   C.E.M. Biotronik, S.A.
Recruiting - verified February 2014

Physical Activity Daily - An Internet-Based Walking Program for Patients With Peripheral Arterial Disease

Condition:   Peripheral Arterial Disease
Interventions:   Behavioral: Supervised PAD rehab;   Behavioral: Internet-based walking program
Sponsors:   University of Michigan;   National Institute on Aging (NIA)
Not yet recruiting - verified April 2014

EYESHOT (EmploYEd Antithrombotic Therapies in Patients With Acute Coronary Syndromes HOspitalized in iTalian Coronary Care Units)

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsors:   Heart Care Foundation;   Centro Servizi ANMCO S.r.l.;   AstraZeneca
Completed - verified March 2014

HsTnT in Stable Coronary Artery Disease

Condition:   Coronary Artery Disease
Intervention:   Other: Progress of CHD
Sponsors:   University Hospital Heidelberg;   AstraZeneca
Active, not recruiting - verified April 2014

Artifact-Free High-Resolution Myocardial Perfusion MRI in Subjects With Abnormal Nuclear Myocardial Perfusion Studies

Conditions:   Coronary Artery Disease;   CAD
Interventions:   Drug: regadenoson;   Drug: Optimark®;   Device: Myocardial perfusion MRI
Sponsors:   Cedars-Sinai Medical Center;   Daniel S. Berman;   Astellas Pharma US, Inc.
Recruiting - verified April 2014

In-hospital and Long-term Outcomes for Percutaneous Chronic Total Coronary Occlusion Revascularization in a High-volume, Multi-operator Program

Condition:   Ischemic Heart Disease
Intervention:  
Sponsor:   Piedmont Healthcare
Recruiting - verified April 2014

BIOFLOW III Asia Registry

Conditions:   Coronary Artery Disease;   Myocardial Ischemia;   Diabetes Mellitus Type 1 or 2
Intervention:  
Sponsor:   BIOTRONIK Asia Pacific Pte Ltd
Recruiting - verified February 2014

Correlation Between Coronary and Carotid Atherosclerotic Disease and Links With Clinical Outcomes

Condition:   Vascular Disease
Intervention:  
Sponsor:   Montreal Heart Institute
Recruiting - verified April 2014

BIOFLOW-III Israel Satellite Registry

Conditions:   Coronary Artery Disease;   Myocardial Ischemia;   Diabetes Mellitus Type 1 or 2
Intervention:  
Sponsor:   BIOTRONIK Israel
Recruiting - verified July 2013

BIOFLOW-III Hungary Satellite Registry

Conditions:   Coronary Artery Disease;   Myocardial Ischemia
Intervention:  
Sponsor:   Biotronik Hungária Kft.
Recruiting - verified July 2013

Interleukin-1 Blockade With Canakinumab to Improve Exercise Capacity in Patients With Chronic Systolic Heart Failure and Elevated Hs-CRP

Conditions:   Prior Acute Myocardial Infarction;   Evidence of Systemic Inflammation (C Reactive Protein Plasma >2 mg/l);   Reduced Left Ventricle Ejection Fraction (<50%);   Symptoms of Heart Failure (NYHA Class II-III)
Interventions:   Other: Cardiopulmonary exercise test;   Other: Echocardiogram
Sponsors:   Virginia Commonwealth University;   Novartis Pharmaceuticals
Active, not recruiting - verified April 2014

Walnut Consumption, Endothelial Function, and Biomarkers

Conditions:   Coronary Heart Disease;   Type 2 Diabetes
Intervention:   Other: Once ounce per day of walnuts
Sponsor:   Brigham and Women's Hospital
Recruiting - verified April 2014

BIOFLOW-III Canada Satellite Registry

Conditions:   Coronary Artery Disease;   Myocardial Ischemia
Intervention:  
Sponsor:   Biotronik Canada Inc
Not yet recruiting - verified June 2013

Application for Self-Monitoring of Cardiovascular Risk

Condition:   Coronary Artery Disease Which Requires Percutaneous Coronary Intervention(Balloon and/or Stent Treatment).
Intervention:   Device: Self Monitoring Software Application
Sponsor:   Mayo Clinic
Recruiting - verified April 2014

Cerebral Oximetry and Perioperative Outcome in Non-Cardiac Surgery

Conditions:   High Risk Non-cardiac Surgery;   Death;   Delirium;   Kidney Injury;   Myocardial Infarction;   Respiratory Failure;   Postoperative Infection
Intervention:   Other: Observational study
Sponsors:   University of Manitoba;   Canadian Anesthesia Research Foundation;   University of Manitoba Department of Anesthesia
Not yet recruiting - verified April 2014

Effects of Linagliptin on Renal Endothelium Function in Patients With Type 2 Diabetes.

Condition:   Type 2-diabetes
Interventions:   Drug: Linagliptin;   Drug: Placebo
Sponsor:   University of Erlangen-Nürnberg Medical School
Completed - verified April 2014

GLobal Assessment of Plaque reGression With a PCSK9 antibOdy as Measured by intraVascular Ultrasound

Condition:   Hypercholesterolemia
Interventions:   Drug: Evolocumab (AMG 145);   Other: Placebo
Sponsor:   Amgen
Recruiting - verified April 2014

Intranasal Insulin: A Novel Treatment for Gulf War Multisymptom Illness

Condition:   Chronic Multisymptom Illness in Gulf War Veterans
Intervention:   Device: Intranasal Insulin
Sponsors:   Bronx Veterans Medical Research Foundation, Inc;   VA Boston Healthcare System;   Boston University
Not yet recruiting - verified April 2014

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease

Condition:   Prevention & Control
Interventions:   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Rivaroxaban (Xarelto, BAY59-7939);   Drug: Aspirin;   Drug: Aspirin placebo;   Drug: Rivaroxaban placebo;   Drug: Pantoprazole
Sponsors:   Bayer;   Hamilton Health Sciences Corporation, Population Health Research Institute
Recruiting - verified April 2014

A Study of Allogeneic Mesenchymal Bone Marrow Cells in Subjects With ST Segment Elevation Myocardial Infarction (STEMI)

Conditions:   ST Segment Elevation Myocardial Infarction (STEMI);   Allogeneic Mesenchymal Bone Marrow Cells
Intervention:   Biological: Stem cells
Sponsors:   Stemedica Cell Technologies, Inc.;   Mercy Gilbert Medical Center at AZ;   Chandler Regional Medical Center at Chandler AZ;   University of California, San Diego
Recruiting - verified April 2014

Tailored Antiplatelet Therapy Following PCI

Conditions:   Coronary Artery Disease;   Acute Coronary Syndrome;   Stenosis
Interventions:   Drug: Clopidogrel;   Drug: Ticagrelor;   Genetic: Retrospective Genotype testing;   Genetic: Prospective Genotype testing
Sponsors:   Mayo Clinic;   Applied Health Research Centre (AHRC), Toronto, Canada
Recruiting - verified April 2014

Randomized Clinical Trial of Intravenous Infusion Umbilical Cord Mesenchymal Stem Cells on Cardiopathy

Condition:   Dilated Cardiomyopathy
Interventions:   Biological: ucMSC;   Other: Controls
Sponsor:   Universidad Los Andes
Recruiting - verified April 2014

Copenhagen Study of Obese Patients With Ischemic Heart Disease Undergoing Low Energy Diet or Interval Training

Conditions:   Ischemic Heart Disease;   Obesity
Interventions:   Other: Interval Training;   Other: Weight Loss
Sponsors:   Bispebjerg Hospital;   Eva Prescott;   University of Copenhagen;   Amager Hospital;   Copenhagen University Hospital at Herlev;   Copenhagen University Hospital, Hvidovre;   Rigshospitalet, Denmark;   University of California, Davis;   Texas A&M University;   University of Aarhus
Completed - verified April 2014

A Study to Evaluate the Effect of Aleglitazar on Cardiac Energetics and Function in Patients With Type 2 Diabetes Mellitus and no History of Coronary Artery Disease

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: aleglitazar;   Drug: placebo
Sponsor:   Hoffmann-La Roche
Completed - verified April 2014

BIOFLOW-III Austria Satellite Registry

Conditions:   Coronary Artery Disease;   Myocardial Ischemia
Intervention:  
Sponsor:   Biotronik Vertriebs-GmbH
Recruiting - verified April 2013

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab SAR236553 (REGN727)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: alirocumab SAR236553 (REGN727);   Other: placebo
Sponsors:   Sanofi;   Regeneron Pharmaceuticals
Recruiting - verified April 2014

Exercise and Low-Dose Rapamycin in Older Adults With CAD:Cardiac Rehabilitation And Rapamycin in Elderly (CARE) Trial

Conditions:   Aging;   CAD
Intervention:   Drug: Rapamycin
Sponsor:   Mayo Clinic
Recruiting - verified April 2014

Invasive vs Conservative Strategies in Non-ST-elevation Acute Coronary Syndrome and Comorbidities

Condition:   Acute Coronary Syndrome
Intervention:   Procedure: Coronary angiogram
Sponsors:   University of Valencia;   Instituto de Salud Carlos III
Active, not recruiting - verified April 2014

Estimation of the Long Term Effectiveness of Routine Use of Cardiac Shock Wave Therapy

Condition:   Coronary Heart Disease (CHD)
Interventions:   Other: Treatment of CHD risk factors;   Drug: Aspirin, Isosorbide mononitrate, Atenolol, Enalapril.;   Drug: Aspirin, Isosorbide mononitrate, Atenolol, Enalapril.;   Procedure: PCA;   Procedure: CABG;   Device: Cardiospec;   Drug: Aspirin, Isosorbide mononitrate, Atenolol, Enalapril
Sponsor:   City Hospital No 40, Saint Petersburg, Russia
Withdrawn - verified April 2014

Omacor Plus Standard Therapies In Post Myocardial Infarction (MI) Subjects Evaluation: The OPTIMISE Observational Study

Condition:   Myocardial Infarction (MI)
Intervention:  
Sponsor:   Abbott
Active, not recruiting - verified April 2014

A Pivotal Trial to Establish the Efficacy and Long-term Safety of the Parachute Implant System

Conditions:   Congestive Heart Failure;   Left Ventricular (LV) Systolic Dysfunction
Intervention:   Device: CardioKinetix Parachute Implant and All Appropriate Medical Therapy (AAMT)
Sponsor:   CardioKinetix, Inc
Recruiting - verified March 2014

A Phase II Study of the Safety and Efficacy of MPSK3169A in Patients With Coronary Heart Disease or High Risk of Coronary Heart Disease

Condition:   Coronary Heart Disease
Interventions:   Drug: MPSK3169A;   Drug: Placebo;   Drug: MPSK3169A;   Drug: MPSK3169A;   Drug: MPSK3169A;   Drug: MPSK3169A
Sponsor:   Genentech
Completed - verified April 2014

ProspEctive First Evaluation in Chest Pain Trial

Conditions:   Chest Pain;   Shortness of Breath;   Suspected Acute Coronary Syndrome
Interventions:   Procedure: Coronary CT Angiography;   Procedure: Stress Test
Sponsor:   St. Luke's-Roosevelt Hospital Center
Recruiting - verified May 2012

A Post Marketing Surveillance to Evaluate the Safety and Efficacy of Brilinta

Condition:   Acute Coronary Syndromes
Intervention:  
Sponsor:   AstraZeneca
Recruiting - verified April 2014

Hormone Therapy, Radiation Therapy, and Steroid 17alpha-monooxygenase TAK-700 in Treating Patients With High-Risk Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: bicalutamide;   Drug: buserelin;   Drug: flutamide;   Drug: goserelin acetate;   Drug: leuprolide acetate;   Drug: orteronel;   Drug: triptorelin
Sponsors:   Radiation Therapy Oncology Group;   National Cancer Institute (NCI)
Recruiting - verified April 2014

Comparison of Drug Eluting Balloon and Drug Eluting Stent

Conditions:   Coronary Artery Disease;   Stable Angina;   Unstable Angina;   NSTEMI
Interventions:   Device: Drug eluting balloon + Bare metal stent;   Device: drug eluting stent (Zotarolimus-eluting stent)
Sponsor:   Seoul National University Bundang Hospital
Recruiting - verified April 2014

Vitamin K to Attenuate Coronary Artery Calcification in Hemodialysis Patients

Condition:   Endstage Kidney Disease
Interventions:   Drug: Vitamin K1;   Drug: Chrystalline Lactose
Sponsors:   Clinical Evaluation Research Unit at Kingston General Hospital;   Dr. Rachel Holden;   Kingston General Hospital
Recruiting - verified April 2014

Evaluating Cardiovascular Phenotypes Using Induced Pluripotent Stem Cells

Condition:   Coronary Artery Disease
Intervention:  
Sponsor:   Scripps Translational Science Institute
Enrolling by invitation - verified April 2014

A Study of Dalcetrapib in Patients With Stable Coronary Heart Disease, With Coronary Heart Disease Risk Equivalents or at Elevated Risk for Cardiovascular Disease

Condition:   Cardiovascular Disease, Coronary Heart Disease, Dyslipidemia, Peripheral Arterial Disease (PAD)
Interventions:   Drug: dalcetrapib;   Drug: Placebo;   Other: Background care
Sponsor:   Hoffmann-La Roche
Completed - verified April 2014

Intracoronary Administration of Levosimendan in Cardiac Surgery Patients

Condition:   Myocardial Stunning
Interventions:   Drug: levosimendan;   Drug: Vitamin B 12
Sponsor:   Tampere University Hospital
Recruiting - verified April 2014

A Study of the Safety and Efficacy of Two Different Regimens of Mipomersen in Patients With Familial Hypercholesterolemia and Inadequately Controlled Low-Density Lipoprotein Cholesterol

Conditions:   Hypercholesterolemia;   Heterozygous Familial
Interventions:   Drug: mipomersen sodium 200 mg;   Drug: Placebo;   Drug: mipomersen sodium 70 mg
Sponsors:   Sanofi;   Genzyme, a Sanofi Company
Active, not recruiting - verified April 2014

Prevention of Serious Adverse Events Following Angiography

Conditions:   Acute Renal Failure;   Kidney Disease;   Coronary Artery Disease
Interventions:   Drug: IV isotonic saline;   Drug: IV isotonic bicarbonate;   Drug: N-acetylcysteine;   Drug: Placebo
Sponsors:   Department of Veterans Affairs;   The George Institute
Recruiting - verified April 2014

A Study to Evaluate Fenofibrate Combination With Statin in Chinese Patients With Dyslipidemic

Conditions:   Dyslipidemias;   Cardiovascular Diseases;   Hypertriglyceridemia
Intervention:   Drug: fenofibrate
Sponsors:   Abbott;   RUNDO International Pharmaceuticals Research & Development Co., Ltd
Completed - verified April 2014

Risk Factors for Coronary Artery Calcification and Left Ventricular Hypertrophy in Hemodialysis Patients

Condition:   End Stage Renal Disease
Intervention:  
Sponsors:   University of Alberta;   Massachusetts General Hospital
Recruiting - verified April 2014

Clearance Of Mucus In Stents

Conditions:   Lung Neoplasms;   Respiratory Failure;   Pneumonia;   Acute Coronary Syndromes;   Unstable Angina;   Myocardial Infarction;   Cardiac Arrhythmia;   Thromboembolic Disease
Interventions:   Other: Normal Saline;   Other: Sodium Bicarbonate
Sponsor:   M.D. Anderson Cancer Center
Recruiting - verified April 2014

Correlation Between Coronary and Carotid Atherosclerotic Disease (CAD) and Links With Clinical Outcomes

Condition:   Atherosclerosis
Intervention:  
Sponsors:   Canadian Atherosclerosis Imaging Network;   Canadian Institutes of Health Research (CIHR)
Recruiting - verified April 2014

ACToR-study : Angiographic CT of Renal Transplantation Candidate - Study

Conditions:   Renal Transplant Candidate for Right Kidney;   Renal Transplant Candidate for Left Kidney
Intervention:  
Sponsor:   University of Aarhus
Completed - verified February 2014

A Study of Dalcetrapib in Patients Hospitalized For An Acute Coronary Syndrome (Dal-ACUTE)

Condition:   Coronary Heart Disease
Interventions:   Drug: dalcetrapib;   Drug: placebo
Sponsor:   Hoffmann-La Roche
Completed - verified April 2014

A Study of RO4905417 in Patients With Non ST-Elevation Myocardial Infarction (Non-STEMI) Undergoing Percutaneous Coronary Intervention

Condition:   Myocardial Infarction
Interventions:   Drug: RO4905417;   Drug: RO4905417;   Drug: placebo;   Procedure: Percutaneous Coronary Intervention (PCI)
Sponsor:   Hoffmann-La Roche
Completed - verified April 2014

Xenon Compared to Sevoflurane and Total Intravenous Anaesthesia for Coronary Artery Bypass Graft Surgery

Conditions:   Coronary Artery Disease;   General Anesthetic Drug Allergy;   Coronary Artery Bypass Graft Surgery
Interventions:   Drug: Xenon;   Drug: Sevoflurane;   Drug: Propofol
Sponsors:   Air Liquide Santé International;   Orion Corporation, Orion Pharma
Completed - verified April 2014

XIENCE V Everolimus Eluting Coronary Stent System (EECSS) China: Post-Approval, Single-Arm Study

Conditions:   Angioplasty;   Chronic Coronary Occlusion;   Stent Thrombosis;   Vascular Disease;   Myocardial Ischemia;   Coronary Artery Stenosis;   Coronary Disease;   Coronary Artery Disease;   Coronary Restenosis
Intervention:   Device: XIENCE V® Everolimus Eluting Coronary Stent System (EECSS)
Sponsor:   Abbott Vascular
Active, not recruiting - verified April 2014

EXCEL Clinical Trial

Conditions:   Chronic Coronary Occlusion;   Unprotected Left Main Coronary Artery Disease;   Stent Thrombosis;   Vascular Disease;   Myocardial Ischemia;   Coronary Artery Stenosis;   Coronary Disease;   Coronary Artery Disease;   Coronary Restenosis
Interventions:   Device: Percutaneous Coronary Intervention;   Procedure: CABG
Sponsor:   Abbott Vascular
Active, not recruiting - verified April 2014

Randomized MicroPort's Firehawk DES Versus Xience V

Condition:   Coronary Artery Disease
Intervention:   Procedure: DES implantation
Sponsor:   MicroPort Medical (Shanghai) Co. Ltd.
Active, not recruiting - verified April 2014

Carpentier-Edwards PERIMOUNT Magna Ease Pericardial Bioprosthesis, Model 3300TFX

Conditions:   Coronary Artery Disease;   Aortic Valve Disorder;   Heart Failure;   Aortic Valve Stenosis;   Aortic Valve Insufficiency
Intervention:   Device: Implantation of CEP Magna Ease Model 3300TFX
Sponsor:   Edwards Lifesciences
Active, not recruiting - verified October 2012

Trial of Atorvastatin on the Persistent Coronary Aneurysm in Children With Kawasaki Disease

Conditions:   Kawasaki Disease;   Aneurysm, Coronary
Intervention:   Drug: Atorvastatin
Sponsors:   National Taiwan University Hospital;   National Science Council, Taiwan
Recruiting - verified April 2014

Rubidium-82 - An Alternative Radiopharmaceutical for Myocardial Imaging(Rb-ARMI)

Condition:   Coronary Artery Disease
Intervention:   Other: Myocardial perfusion imaging using Rb-82 PET or Tc-99m or Tl SPECT
Sponsors:   University of Ottawa Heart Institute;   Canadian Institutes of Health Research (CIHR)
Active, not recruiting - verified April 2014

XIENCE V/PROMUS Everolimus-Eluting Stent System Post-marketing Surveillance Protocol for Japan

Conditions:   Angina;   Chronic Coronary Occlusion;   Stent Thrombosis;   Vascular Disease;   Myocardial Ischemia;   Coronary Artery Stenosis;   Coronary Disease;   Coronary Artery Disease;   Coronary Restenosis
Intervention:   Device: XIENCE V / PROMUS stent placement
Sponsor:   Abbott Vascular
Active, not recruiting - verified April 2014

A Study of the Effect of Dalcetrapib on Artherosclerotic Disease in Patients With Coronary Artery Disease

Condition:   Cardiovascular Disease
Interventions:   Drug: dalcetrapib;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Terminated - verified April 2014

Care Transitions for Complex Patient - Cycle 1 and Cycle 2

Conditions:   Asthma;   Coronary Artery Disease;   Diabetes;   Hypertension;   Congestive Heart Failure
Interventions:   Other: Reports;   Other: Reports and Notices;   Other: Usual care
Sponsors:   Duke University;   Northern Piedmont Carolina Community Care Partners;   North Carolina Division of Medical Assistance
Completed - verified February 2014

AFRICA: Atorvastatin Plus Fenofibric Acid (TriLipix) in the Reduction of Intermediate Coronary Atherosclerosis

Condition:   Coronary Atherosclerosis
Interventions:   Drug: Placebo;   Drug: TriLipix
Sponsor:   Piedmont Healthcare
Terminated - verified April 2014

Molecular and Morphologic Characterization of Circulating Endothelial Cells

Condition:   Acute Myocardial Infarction
Intervention:  
Sponsor:   Scripps Translational Science Institute
Recruiting - verified April 2014

Individualized Comprehensive Atherosclerosis Risk-reduction Evaluation Program

Condition:   Atherosclerosis
Intervention:  
Sponsors:   Piedmont Healthcare;   Abbott
Recruiting - verified April 2014

De Novo Pilot Study, Lutonix Catheter in Conjunction With Bare Metal Stenting for Treatment of Coronary De Novo Lesions

Condition:   Coronary Artery Stenosis
Intervention:   Device: Lutonix Paclitaxel-Coated Balloon
Sponsor:   C. R. Bard
Completed - verified April 2014

BAY81-8781, I.V. Aspirin in the Indication of Acute Coronary Syndrome (ACS)

Condition:   Acute Coronary Syndrome
Interventions:   Drug: Acetylsalicylic acid (Aspirin, BAY 81-8781);   Drug: Acetylsalicylic acid (Aspirin, BAY 81-8781);   Drug: Acetylsalicylic acid (Aspirin, BAY 81-8781)
Sponsor:   Bayer
Recruiting - verified April 2014

Detection of Subclinical Atherosclerosis in Asymptomatic Individuals

Condition:   Coronary Artery Disease
Intervention:   Procedure: Cardiac CT
Sponsor:   Piedmont Healthcare
Recruiting - verified April 2014

Magna® Mitral Pericardial Bioprostheses Post-Approval Study Protocol

Conditions:   Coronary Artery Disease;   Mitral Valve Regurgitation;   Mitral Valve Incompetence;   Heart Failure
Intervention:   Device: CEP MAGNA MITRAL PERICARDIAL BIOPROSTHESES
Sponsor:   Edwards Lifesciences
Recruiting - verified April 2014

Validation of Stenosis Assessment by Coronary Artery Computed Tomography Against Invasive Measurements of Fractional Flow Reserve in Patients With Significant Coronary Artery Stenoses

Condition:   Coronary Artery Stenosis
Intervention:   Procedure: FFR, IVUS, VH, or combination of the three
Sponsor:   Piedmont Healthcare
Completed - verified April 2014

Comparing the Effectiveness of Repairing Versus Replacing the Heart's Mitral Valve in People With Severe Chronic Ischemic Mitral Regurgitation

Conditions:   Mitral Valve Insufficiency;   Coronary Artery Disease
Interventions:   Procedure: Mitral Valve Repair with Annuloplasty;   Procedure: Mitral Valve Replacement
Sponsors:   Mount Sinai School of Medicine;   National Heart, Lung, and Blood Institute (NHLBI);   Canadian Institutes of Health Research (CIHR);   National Institute of Neurological Disorders and Stroke (NINDS)
Active, not recruiting - verified April 2014

Comparing the Effectiveness of a Mitral Valve Repair Procedure in Combination With Coronary Artery Bypass Grafting (CABG) Versus CABG Alone in People With Moderate Ischemic Mitral Regurgitation

Conditions:   Mitral Valve Insufficiency;   Coronary Artery Disease
Interventions:   Procedure: Mitral Valve Repair;   Procedure: CABG
Sponsors:   Mount Sinai School of Medicine;   National Heart, Lung, and Blood Institute (NHLBI);   Canadian Institutes of Health Research (CIHR);   National Institute of Neurological Disorders and Stroke (NINDS)
Active, not recruiting - verified April 2014

Choice Of Optimal Strategy For Bifurcation Lesions With Normal Side Branch

Condition:   Coronary Artery Disease
Interventions:   Procedure: kissing balloon;   Procedure: without kissing balloon angioplasty "leave alone"
Sponsors:   CardioVascular Research Foundation, Korea;   Seung-Jung Park
Completed - verified April 2014

Prospective Observational Epidemiologic Study of Maraviroc's Safety

Condition:   Human Immunodeficiency Virus
Interventions:   Drug: Maraviroc along with an optimized background antiretroviral drug regimen;   Drug: Optimized background antiretroviral drug regimen without maraviroc
Sponsors:   ViiV Healthcare;   Pfizer
Active, not recruiting - verified April 2014

A Study of the Effect of RO4607381 on Atherosclerotic Plaque in Patients With Coronary Heart Disease

Condition:   Coronary Heart Disease
Interventions:   Drug: dalcetrapib;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Completed - verified April 2014

A Study Assessing the Effect of RO4607381 on Vascular Function in Patients With Coronary Heart Disease (CHD) or CHD-Risk Equivalent Patients

Condition:   Coronary Heart Disease
Interventions:   Drug: dalcetrapib;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Completed - verified April 2014

Prevention of Contrast Nephropathy During Diagnostic Coronary Angiogram or PCI With Hydratation Based on LEVDP

Conditions:   Radiographic Contrast Agent Nephropathy;   Renal Failure;   Coronary Heart Disease
Interventions:   Drug: Normal saline and sodium bicarbonate;   Drug: normal saline;   Drug: Sodium bicarbonate
Sponsor:   Université de Sherbrooke
Recruiting - verified April 2014

Risk Reduction in Coronary Heart Disease

Condition:   Coronary Heart Disease
Interventions:   Behavioral: smoking cessation;   Drug: betablocker, diuretics, ACEI, ARB,;   Drug: statins, ezetimibe;   Behavioral: training;   Biological: influenza vaccine;   Drug: metformin, glimepiride, insulin;   Behavioral: weight reduction
Sponsors:   Sorlandet Hospital HF;   Oslo University Hospital
Recruiting - verified April 2014

A Long Term Extension of Study NC19453 Evaluating Safety and Efficacy of RO4607381

Condition:   Coronary Heart Disease
Interventions:   Drug: dalcetrapib;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Completed - verified April 2014

Strategies to Maintain Cardiac Risk Control After Discharge From Cardiovascular Risk Reduction Clinic

Conditions:   Diabetes;   Dyslipidemia;   Hypertension;   Coronary Atherosclerosis
Interventions:   Behavioral: Counseling;   Behavioral: Interactive Education;   Behavioral: Group Support;   Procedure: Pharmacologic case management
Sponsors:   Providence VA Medical Center;   Merck Sharp & Dohme Corp.
Completed - verified April 2014

A Study of RO4607381 in Patients With Coronary Heart Disease (CHD) or a CHD Risk Equivalent.

Condition:   Coronary Heart Disease
Interventions:   Drug: dalcetrapib;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Completed - verified April 2014

Healthy Endothelial Accelerated Lining Inhibits Neointimal Growth

Conditions:   Coronary Artery Disease;   Coronary Artery Stenosis
Intervention:   Device: Coronary stent implantation
Sponsor:   OrbusNeich
Completed - verified April 2014

Cell Repair in Heart Failure

Conditions:   Heart Failure;   Ischemia
Intervention:   Procedure: Retrograde coronary venous delivery of cells.
Sponsor:   Imperial College London
Withdrawn - verified February 2006

Hypertension Intervention Nurse Telemedicine Study (HINTS)

Condition:   Hypertension
Interventions:   Behavioral: Nurse Behavioral intervention with Home BP Telemonitoring;   Behavioral: Nurse Medication Management with Home BP Telemonitoring;   Behavioral: Nurse Combined intervention with Home BP Telemonitoring
Sponsor:   Department of Veterans Affairs
Completed - verified April 2014

Collaborative Cardiac Care Project

Conditions:   Myocardial Ischemia;   Angina Pectoris;   Coronary Disease
Interventions:   Procedure: Collaborative care model;   Procedure: Group interventions;   Procedure: Facilitated consultation
Sponsor:   Department of Veterans Affairs
Completed - verified April 2014

Nurses' Health Study (Cardiovascular Component)

Conditions:   Cardiovascular Diseases;   Diabetes Mellitus;   Coronary Disease;   Heart Diseases;   Cerebrovascular Accident;   Pulmonary Embolism;   Angina Pectoris;   Myocardial Infarction;   Menopause;   Postmenopause
Intervention:  
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI)
Completed - verified April 2014

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