Mitral Valve Regurgitation

Clinical Trial Finder

Many patients with mitral valve regurgitation are interested in participating in the latest research regarding their condition. This Clinical Trial Finder can help you—or a loved one—easily find ongoing cardiovascular clinical research trials for which you might qualify. This list is a service of the U.S. National Institutes of Health called clinicaltrials.gov, a database of publicly and privately supported clinical studies.

Simply click on the trial below that interests you to learn how you might participate.

Assessment of Changes in Metabolic Activity in Liver & Skeletal Muscle in Patients Suffering From Acromegaly

Condition:   Acromegaly
Interventions:   Other: 1H/31P Magnetic Resonance Spectroscopy;   Other: oral glucose tolerance testing;   Other: Thyroid sonography
Sponsor:   Medical University of Vienna
Not yet recruiting - verified April 2014

The Role of Dopaminergic and Glutamatergic Neurotransmission for Dysfunctional Learning in Alcohol Use Disorders

Condition:   Alcohol Use Disorder
Intervention:   Other: Alcohol detoxification
Sponsors:   Technische Universität Dresden;   Charite University, Berlin, Germany
Enrolling by invitation - verified April 2014

Comparison Between Hand-acupuncture and Electro-acupuncture Stimulation in the Treatment of Menopause

Conditions:   Menopause;   Puncture Site Reaction
Interventions:   Behavioral: Hand-acupuncture;   Device: Electrico-acupuncture
Sponsors:   The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine;   The Affiliated Hospital of the Chinese Academy of Military Medical Sciences
Recruiting - verified March 2014

A Study of the Efficacy and Safety of Activase (Alteplase) in Patients With Mild Stroke (PRISMS)

Condition:   Brain Ischemia
Interventions:   Drug: alteplase [Activase];   Drug: alteplase placebo;   Drug: aspirin;   Drug: aspirin placebo
Sponsor:   Genentech
Recruiting - verified April 2014

High-field Brain Magnetic Resonance Spectroscopy

Condition:   Healthy
Intervention:  
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   National Institute for Biomedical Imaging and Bioengineering (NIBIB)
Active, not recruiting - verified April 2014

Treatment Differences Between Canagliflozin and Placebo in Insulin Secretion in Subjects With Type 2 Diabetes Mellitus (T2DM)

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Canagliflozin, 100 mg;   Drug: Canagliflozin, 300 mg;   Drug: Placebo
Sponsor:   Janssen Research & Development, LLC
Not yet recruiting - verified April 2014

Proton MR Spectroscopy and 18F-Fluorocholine PET for Breast Cancer Diagnosis

Conditions:   Breast Cancer Diagnosis;   Positron Emission Tomography;   Magnetic Resonance Imaging
Interventions:   Drug: 18F-FCH;   Drug: Magnevist
Sponsor:   National Taiwan University Hospital
Recruiting - verified April 2014

A Study to Evaluate the Effect of Aleglitazar on Cardiac Energetics and Function in Patients With Type 2 Diabetes Mellitus and no History of Coronary Artery Disease

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: aleglitazar;   Drug: placebo
Sponsor:   Hoffmann-La Roche
Completed - verified April 2014

DaTSCAN Imaging in Aging and Neurodegenerative Disease

Conditions:   Dementia;   Parkinsonism;   Mild Cognitive Impairment;   REM Sleep Behavior Disorder
Interventions:   Drug: I-123 Ioflupane solution injection prior to SPECT scan (DaTscan);   Device: Single photon emission computed tomography (SPECT) scan
Sponsor:   Mayo Clinic
Enrolling by invitation - verified April 2014

Physical Fitness, Cardiovascular and Brain Health

Condition:   Hypertension
Interventions:   Behavioral: Aerobic Exercise;   Behavioral: Relaxation
Sponsors:   University of Texas at Austin;   American Federation for Aging Research
Completed - verified April 2014

A Study of RO5093151 in Patients With Non-Alcoholic Fatty Liver Disease

Condition:   Fatty Liver, Non-alcoholic Fatty Liver Disease, NAFLD
Interventions:   Drug: RO5093151;   Drug: Placebo
Sponsor:   Hoffmann-La Roche
Completed - verified April 2014

A Clinical Trial of Exendin-4 for the Treatment of Alzheimer's Disease

Condition:   Alzheimer's Disease
Intervention:   Drug: Exendin-4 (Exenatide)
Sponsors:   National Institutes of Health Clinical Center (CC);   National Institute on Aging (NIA)
Recruiting - verified August 2013

Magna® Mitral Pericardial Bioprostheses Post-Approval Study Protocol

Conditions:   Coronary Artery Disease;   Mitral Valve Regurgitation;   Mitral Valve Incompetence;   Heart Failure
Intervention:   Device: CEP MAGNA MITRAL PERICARDIAL BIOPROSTHESES
Sponsor:   Edwards Lifesciences
Recruiting - verified April 2014

Comparing the Effectiveness of a Mitral Valve Repair Procedure in Combination With Coronary Artery Bypass Grafting (CABG) Versus CABG Alone in People With Moderate Ischemic Mitral Regurgitation

Conditions:   Mitral Valve Insufficiency;   Coronary Artery Disease
Interventions:   Procedure: Mitral Valve Repair;   Procedure: CABG
Sponsors:   Mount Sinai School of Medicine;   National Heart, Lung, and Blood Institute (NHLBI);   Canadian Institutes of Health Research (CIHR);   National Institute of Neurological Disorders and Stroke (NINDS)
Active, not recruiting - verified April 2014

Comparing the Effectiveness of Repairing Versus Replacing the Heart's Mitral Valve in People With Severe Chronic Ischemic Mitral Regurgitation

Conditions:   Mitral Valve Insufficiency;   Coronary Artery Disease
Interventions:   Procedure: Mitral Valve Repair with Annuloplasty;   Procedure: Mitral Valve Replacement
Sponsors:   Mount Sinai School of Medicine;   National Heart, Lung, and Blood Institute (NHLBI);   Canadian Institutes of Health Research (CIHR);   National Institute of Neurological Disorders and Stroke (NINDS)
Active, not recruiting - verified April 2014

Non-Invasive Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopy Techniques (MRS) for Assessing Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer

Condition:   Breast Cancer
Interventions:   Procedure: Magnetic Resonance Imaging (MRI);   Procedure: Magnetic Resonance Spectroscopy (MRS)
Sponsors:   M.D. Anderson Cancer Center;   National Cancer Institute (NCI)
Active, not recruiting - verified April 2014

Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan Syndrome--Pediatric Heart Network

Condition:   Marfan Syndrome
Interventions:   Drug: Losartan Potassium;   Drug: Atenolol
Sponsors:   New England Research Institutes;   National Heart, Lung, and Blood Institute (NHLBI);   FDA Office of Orphan Products Development;   National Marfan Foundation
Completed - verified January 2014

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