To survive and grow, cancer tumors depend on blood vessels supplying oxygen and nutrition. The growth of blood vessels, which is called angiogenesis, also helps cancer tumors spread to other areas of the body.
That is why cancer treatment often includes therapies to block the growth of blood vessels. These agents are also known as anti-angiogenic therapies. Some health care providers may refer to some of these anti-angiogenic therapies as vascular endothelial growth factor inhibitors (VEGF inhibitors) or tyrosine kinase inhibitors (TKIs).
Authors: Wendy Bottinor, MD; Carrie Geisberg Lenneman, MD, MSc
Reviewers: Debra Madden, BA; Bonnie Ky, MD, MSCE